TargetMol

Angiotensin II human

Product Code:
 
TAR-T7040
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7040-5mg5mg£102.00
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TAR-T7040-10mg10mg£119.00
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TAR-T7040-25mg25mg£178.00
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TAR-T7040-50mg50mg£269.00
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TAR-T7040-100mg100mg£328.00
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Further Information

Bioactivity:
Angiotensin II is mediated by AT1 and AT2 receptors. AT1 and AT2 receptors have seven transmembrane glycoproteins with 30% sequence similarity.Angiotensin I convert Angiotensin II human through removing of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE).
CAS:
4474-91-3
Formula:
C50H71N13O12
Molecular Weight:
1046.197
Pathway:
Apoptosis; Endocrinology/Hormones
Purity:
0.9986
SMILES:
CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc1cnc[nH]1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(O)=O
Target:
Apoptosis; RAAS

References

Zhang R Y, Wu C M, Hu X M, et al. LncRNA AC105942. 1 Downregulates hnRNPA2/B1 to Attenuate Vascular Smooth Muscle Cells Proliferation[J]. DNA and Cell Biology. 2021 Zhang L, Zhang B, Yu Y, et al. Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload[J]. International Heart Journal. 2021: 20-384 Zhang L, Zhang B, Yu Y, et al. Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload. International Heart Journal. 2021: 20-384 Zhang R Y, Wu C M, Hu X M, et al. LncRNA AC105942. 1 Downregulates hnRNPA2/B1 to Attenuate Vascular Smooth Muscle Cells Proliferation. DNA and Cell Biology. 2021 Fyhrquist F, et al. Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders. J Hum Hypertens. 1995 Nov;9 Suppl 5:S19-24. Crowley SD, et al. Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):171985-90. de Gasparo M, et al. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev. 2000 Sep;52(3):415-72.