TargetMol

2BAct

Product Code:
 
TAR-T9149
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T9149-1mg1mg£142.00
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TAR-T9149-5mg5mg£249.00
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TAR-T9149-1mL1 mL * 10 mM (in DMSO)£279.00
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TAR-T9149-10mg10mg£356.00
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TAR-T9149-25mg25mg£544.00
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TAR-T9149-50mg50mg£747.00
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Quantity:
TAR-T9149-100mg100mg£978.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response
CAS:
2143542-28-1
Formula:
C19H16ClF3N4O3
Molecular Weight:
440.81
Pathway:
Apoptosis
Purity:
0.9797
SMILES:
FC(F)c1cnc(cn1)C(=O)NC12CC(C1)(C2)NC(=O)COc1ccc(Cl)c(F)c1
Target:
PERK

References

Wong YL, LeBon L, Basso AM, Kohlhaas KL, Nikkel AL, Robb HM, Donnelly-Roberts DL, Prakash J, Swensen AM, Rubinstein ND, Krishnan S, McAllister FE, Haste NV, O'Brien JJ, Roy M, Ireland A, Frost JM, Shi L, Riedmaier S, Martin K, Dart MJ, Sidrauski C. eIF2B activator prevents neurological defects caused by a chronic integrated stress response. Elife. 2019 Jan 9;8. pii. e42940.