TargetMol

Boc-C14-COOH

Product Code:
 
TAR-T9781
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T9781-500mg500mg£96.00
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Further Information

Bioactivity:
Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CAS:
843666-27-3
Formula:
C20H37O4
Molecular Weight:
341.513
Pathway:
PROTAC
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)CCCCCCCCCCCCCCC([O-])=O
Target:
PROTAC Linker

References

Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.