TargetMol

4-Methylamino antipyrine

Product Code:
 
TAR-T10152
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T10152-1mL1 mL * 10 mM (in DMSO)£96.00
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TAR-T10152-10mg10mg£102.00
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TAR-T10152-25mg25mg£138.00
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TAR-T10152-50mg50mg£172.00
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TAR-T10152-100mg100mg£228.00
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TAR-T10152-200mg200mg£310.00
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TAR-T10152-500mg500mg£469.00
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Further Information

Bioactivity:
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relatively weak anti-inflammatory properties.
CAS:
519-98-2
Formula:
C12H15N3O
Molecular Weight:
217.272
Pathway:
Immunology/Inflammation; Metabolism; Neuroscience
Purity:
0.9585
SMILES:
CNc1c(C)n(C)n(-c2ccccc2)c1=O
Target:
COX; Drug Metabolite

References

1. Burma?czuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec;39(6):616-620. 2. Campos C1, et al. Regulation of cyclooxygenase activity by metamizol. Eur J Pharmacol. 1999 Aug 13;378(3):339-47. 3. Ariza A, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016 Mar 31;6:23845.