TargetMol

CD2665

Product Code:
 
TAR-T14911
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14911-1mg1mg£137.00
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TAR-T14911-5mg5mg£205.00
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TAR-T14911-10mg10mg£274.00
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TAR-T14911-25mg25mg£412.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.
CAS:
170355-78-9
Formula:
C31H34O5
Molecular Weight:
486.6
Pathway:
Metabolism
Purity:
0.9967
SMILES:
O=C(O)C=1C=CC(=CC1)C2=CC=C3C=C(OCOCCOC)C(=CC3=C2)C45CC6CC(CC(C6)C4)C5
Target:
Retinoid Receptor

References

1. Kim MJ, et al. The role of specific retinoid receptors in sebocyte growth and differentiation in culture. J Invest Dermatol. 2000 Feb;114(2):349-53. 2. Koyama E, et al.Premature Growth Plate Closure Caused by a Hedgehog Cancer Drug Is Preventable by Co-Administration of a Retinoid Antagonist in Mice. J Bone Miner Res. 2021 Jul;36(7):1387-1402. 3. Alfos S, Boucheron C, et al. A retinoic acid receptor antagonist suppresses brain retinoic acid receptor overexpression and reverses a working memory deficit induced by chronic ethanol consumption in mice. Alcohol Clin Exp Res. 2001 Oct;25(10):1506-14.