TargetMol

Daltroban

Product Code:
 
TAR-T15049
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15049-1mg1mg£201.00
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Quantity:
TAR-T15049-1mL1 mL * 10 mM (in DMSO)£343.00
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TAR-T15049-5mg5mg£422.00
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TAR-T15049-10mg10mg£592.00
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TAR-T15049-25mg25mg£863.00
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TAR-T15049-50mg50mg£1,187.00
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Quantity:
TAR-T15049-100mg100mg£1,572.00
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Quantity:
TAR-T15049-500mg500mg£3,083.00
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Quantity:
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Further Information

Bioactivity:
Daltroban is a specific thromboxane A2 (TXA2) receptor antagonist. Daltroban shows protective effect in reperfusion injury. Daltroban increase intracellular calcium in vascular smooth muscle cells.
CAS:
79094-20-5
Formula:
C16H16ClNO4S
Molecular Weight:
353.82
Pathway:
DNA Damage/DNA Repair|Metabolism
Purity:
0.98
SMILES:
O=C(CC1=CC=C(C=C1)CCNS(=O)(C2=CC=C(C=C2)Cl)=O)O
Target:
PPAR

References

1. Miki I, et al. Differences in activities of thromboxane A2 receptor antagonists in smooth muscle cells. Eur J Pharmacol. 1992 Oct 1;227(2):199-204. 2. Thiemermann C, et al. The thromboxane receptor antagonist, daltroban, protects the myocardium from ischaemic injury resulting in suppression of leukocytosis. Eur J Pharmacol. 1988 Oct 11;155(1-2):57-67. 3. Bhat AM, et al. Protective effect of the specific thromboxane receptor antagonist, BM-13505, in reperfusion injury following acute myocardial ischemia in cats. Am Heart J. 1989 Apr;117(4):799-803.