TargetMol

SL 0101-1

Product Code:
 
TAR-T16896
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16896-10mg10mg£1,595.00
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Further Information

Bioactivity:
SL 0101-1 is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase inhibitor (IC50: 89 nM). It shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase.
CAS:
77307-50-7
Formula:
C25H24O12
Molecular Weight:
516.455
Purity:
0.98
SMILES:
C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2ccc(O)cc2)[C@H](O)[C@H](OC(C)=O)[C@H]1OC(C)=O

References

1. Smith JA, et al. Identification of the first specific inhibitor of p90 ribosomal S6 kinase (RSK) reveals an unexpected role for RSK in cancer cell proliferation. Cancer Res. 2005 Feb 1;65(3):1027-34.