TargetMol

Atorvastatin hemicalcium salt

Product Code:
 
TAR-T3116
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T3116-10mg10mg£107.00
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TAR-T3116-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T3116-25mg25mg£113.00
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TAR-T3116-50mg50mg£119.00
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TAR-T3116-100mg100mg£152.00
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TAR-T3116-200mg200mg£204.00
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Quantity:
TAR-T3116-500mg500mg£321.00
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This product comes from: United States.
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Further Information

Bioactivity:
Atorvastatin hemicalcium salt, an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
CAS:
134523-03-8
Formula:
C66H68CaF2N4O10
Molecular Weight:
1155.363
Pathway:
Metabolism; Cell Cycle/Checkpoint; Apoptosis; Autophagy
Purity:
0.9989
SMILES:
[Ca++].CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CCC(O)CC(O)CC([O-])=O)-c1ccccc1.CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CCC(O)CC(O)CC([O-])=O)-c1ccccc1
Target:
Ferroptosis; HMG-CoA Reductase; Autophagy

References

1. Hern?ndez-Perera O, et al. J Clin Invest. 1998 Jun 15;101(12):2711-9. 2. Zhang L, et al. Am J Physiol Heart Circ Physiol, 2007, 293(1), H457-466. 3. Ortego M, et al. Atherosclerosis, 1999, 147(2), 253-261. 4. Aviram M, et al. Atherosclerosis, 1998, 138(2), 271-280. 5. Rajamannan NM, et al. Circulation, 2002, 105(22), 2660-2665. 6. Li Y, et al. Inhibition of endoplasmic reticulum stress signaling pathway: A new mechanism of statins to suppress the development of abdominal aortic aneurysm. PLoS One. 2017 Apr 3;12(4):e0174821.