TargetMol

Diacerein

Product Code:
 
TAR-T1273
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1273-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1273-50mg50mg£111.00
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Further Information

Bioactivity:
Diacerein is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre diarrhea [L780]. Diacerein is under investigation for the treatment of Insulin Resistance, Diabetes Mellitus (Type 2), and Diabetes-Related Complications.
CAS:
13739-02-1
Formula:
C19H12O8
Molecular Weight:
368.297
Pathway:
Immunology/Inflammation
Purity:
0.9814
SMILES:
CC(=O)Oc1cccc2C(=O)c3cc(cc(OC(C)=O)c3C(=O)c12)C(O)=O
Target:
IL Receptor; Interleukin

References

1. Yaron M, et al. Osteoarthritis Cartilage, 1999, 7(3), 272-280. 2. Felisaz N, et al. Osteoarthritis Cartilage, 1999, 7(3), 255-264. 3. Boileau C, et al. Arthritis Res Ther, 2008, 10(3), R71. 4. Tamura T, et al. Eur J Pharmacol, 2002, 448(1), 81-87. 5. Hwa SY, et al. J Rheumatol, 2001, 28(4), 825-834.