TargetMol

Diosmetin

Product Code:
 
TAR-T1704
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1704-25mg25mg£98.00
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TAR-T1704-50mg50mg£109.00
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TAR-T1704-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1704-100mg100mg£123.00
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This product comes from: United States.
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Further Information

Bioactivity:
Diosmetin has been found to act as a weak TrkB receptor agonist.
CAS:
520-34-3
Formula:
C16H12O6
Molecular Weight:
300.266
Pathway:
Tyrosine Kinase/Adaptors; Metabolism
Purity:
0.98
SMILES:
COc1ccc(cc1O)-c1cc(=O)c2c(O)cc(O)cc2o1
Target:
P45; Trk receptor

References

1. Sher E, et al. Pharmacol Res, 1992, 26(4), 395-402. 2. Morel I, et al. Biochem Pharmacol, 1993, 45(1), 13-19. 3. Ciolino HP, et al. Cancer Res, 1998, 58(13), 2754-2760. 4. Quintieri L, et al. Drug Metab Pharmacokinet, 2011, 26(6), 559-568. 5. Yu G, et al. Diosmetin ameliorates the severity of cerulein-induced acute pancreatitis in mice by inhibiting the activation of the nuclear factor-?B. Int J Clin Exp Pathol. 2014 Apr 15;7(5):2133-42. 6. Liu B, et al. Diosmetin induces apoptosis by upregulating p53 via the TGF-? signal pathway in HepG2 hepatoma cells. Mol Med Rep. 2016 Jul;14(1):159-64.