TargetMol

StA-IFN-1

Product Code:
 
TAR-T38158
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T38158-5mg5mg£850.00
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Quantity:
TAR-T38158-50mg50mg£1,661.00
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Quantity:
TAR-T38158-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective for the IFN induction pathway and not the IFN signaling pathway.
CAS:
300839-31-0
Formula:
C14H13N3O2
Molecular Weight:
255.277
Purity:
0.98
SMILES:
CC(=O)n1cc(C2C(C)=NN=C2O)c2ccccc12