TargetMol

Clemastine fumarate

Product Code:
 
TAR-T0147
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0147-50mg50mg£101.00
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TAR-T0147-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T0147-100mg100mg£111.00
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TAR-T0147-200mg200mg£132.00
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This product comes from: United States.
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Further Information

Bioactivity:
Clemastine Fumarate is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties.
CAS:
14976-57-9
Formula:
C25H30ClNO5
Molecular Weight:
459.97
Pathway:
Neuroscience; Immunology/Inflammation; GPCR/G Protein; Autophagy
Purity:
0.998
SMILES:
OC(=O)C=CC(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1
Target:
Autophagy; Histamine Receptor

References

1. Seifert R, et al. Mol Pharmacol, 1992, 42(2), 227-234. 2. Nair MP, et al. Cell Immunol, 1983, 81(1), 45-60. 3. Merlos M, et al. J Pharmacol Exp Ther, 1997, 280(1), 114-121. 4. Ridley JM, et al. J Mol Cell Cardiol, 2006, 40(1), 107-118. 5. N?renberg W, et al. J Biol Chem, 2011, 286(13), 11067-11081. 6. Xie D, Niu L, Gao C, et al. Clemastine Improves Hypomyelination in Rats with Hypoxic?Ischemic Brain Injury by Reducing Astroglia-Derived IL-1? via Autophagy[J]. 2020.