TargetMol

Lamivudine

Product Code:
 
TAR-T0682
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T0682-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T0682-50mg50mg£113.00
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TAR-T0682-100mg100mg£134.00
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TAR-T0682-500mg500mg£222.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Lamivudine is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat HIV disease.
CAS:
134678-17-4
Formula:
C8H11N3O3S
Molecular Weight:
229.25
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9956
SMILES:
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1
Target:
HIV Protease; Reverse Transcriptase

References

1. Shaw T, et al. J Viral Hepat, 1999, 6(2), 89-106. 2. Colledge D, et al. Hepatology, 1997, 26(1), 216-225. 3. Merrill DP, et al. J Infect Dis, 1996, 173(2), 355-364. 4. Wu Y, Yang J, Duan C, et al. Simultaneous determination of antiretroviral drugs in human hair with liquid chromatography-electrospray ionization-tandem mass spectrometry[J]. Journal of Chromatography B. 2018 Apr 15;1083:209-221. 5. Herrmann A, Roesner M, Werner T, et al. Potent inhibition of HIV replication in primary human cells by novel synthetic polyketides inspired by Aureothin[J]. Scientific Reports. 2020, 10(1): 1-15. 6. Xie B, Sun D, Du Y, et al. A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts[J]. Cell research. 2019: 1.