TargetMol

NSC305787 hydrochloride

Product Code:
 
TAR-T12263L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T12263L-5mg5mg£351.00
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Quantity:
TAR-T12263L-50mg50mg£1,267.00
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Quantity:
TAR-T12263L-100mg100mg£1,669.00
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This product comes from: United States.
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Further Information

Bioactivity:
NSC305787 hydrochloride is an inhibitor of ezrin (Kd: 5.85 μM). NSC305787 hydrochloride inhibits the phosphorylation of ezrin caused by PKC? (IC50: 8.3 μM). It has an antitumor activity.
CAS:
53868-26-1
Formula:
C25H31Cl3N2O
Molecular Weight:
481.89
Purity:
0.98
SMILES:
Cl.OC(C1CCCCN1)c1cc(nc2c(Cl)cc(Cl)cc12)C12CC3CC(CC(C3)C1)C2

References

1. Bulut G, et al. Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells. Oncogene. 2012 Jan 19;31(3):269-81. 2. ?elik H, et al. Ezrin Inhibition Up-regulates Stress Response Gene Expression. J Biol Chem. 2016 Jun 17;291(25):13257-70.