TargetMol

I-BET762 carboxylic acid

Product Code:
 
TAR-T13086
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T13086-100mg100mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T13086-50mg50mgEnquire
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
CAS:
1300019-38-8
Formula:
C20H17ClN4O3
Molecular Weight:
396.83
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
COc1ccc-2c(c1)C(=N[C@@H](CC(O)=O)c1nnc(C)n-21)c1ccc(Cl)cc1
Target:
Epigenetic Reader Domain

References

1. Mirguet O, et al. Discovery of epigenetic regulator I-BET762: lead optimization to afford a clinical candidate inhibitor of the BET bromodomains. J Med Chem. 2013 Oct 10;56(19):7501-15.