TargetMol

Akt1 and Akt2-IN-1

Product Code:
 
TAR-T14152
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14152-5mg5mg£351.00
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TAR-T14152-50mg50mg£1,267.00
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Quantity:
TAR-T14152-100mg100mg£1,669.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
CAS:
893422-47-4
Formula:
C33H29N7O
Molecular Weight:
539.643
Pathway:
PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.98
SMILES:
O=c1[nH]ccc2nc(-c3ccc(CN4CCC(CC4)c4n[nH]c(n4)-c4ccccn4)cc3)c(cc12)-c1ccccc1
Target:
Akt

References

1. Bilodeau MT, Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3178-82.