TargetMol

Apafant

Product Code:
 
TAR-T14300
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T14300-100mg100mgEnquire
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Further Information

Bioactivity:
Apafant is a potent antagonist of platelet-activating factor (PAF), inhibits PAF binding to human PAF receptors(Ki : 9.9 nM).
CAS:
105219-56-5
Formula:
C22H22ClN5O2S
Molecular Weight:
455.96
Purity:
0.98
SMILES:
Cc1nnc2CN=C(c3cc(CCC(=O)N4CCOCC4)sc3-n12)c1ccccc1Cl

References

1. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.