TargetMol

SR2211

Product Code:
 
TAR-T16929
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16929-1mg1mg£106.00
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TAR-T16929-5mg5mg£148.00
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TAR-T16929-1mL1 mL * 10 mM (in DMSO)£169.00
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TAR-T16929-10mg10mg£222.00
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TAR-T16929-25mg25mg£327.00
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TAR-T16929-50mg50mg£452.00
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TAR-T16929-100mg100mg£618.00
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TAR-T16929-500mg500mg£1,187.00
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Further Information

Bioactivity:
SR2211 is a potent and selective synthetic RORγ modulator (Ki: 105 nM and an IC50: ~320 nM).
CAS:
1359164-11-6
Formula:
C26H24F7N3O
Molecular Weight:
527.487
Pathway:
Metabolism
Purity:
0.98
SMILES:
OC(c1ccc(c(F)c1)-c1ccc(CN2CCN(Cc3ccncc3)CC2)cc1)(C(F)(F)F)C(F)(F)F
Target:
ROR

References

1. Kumar N, et al. Identification of SR2211: a potent synthetic ROR?-selective modulator. ACS Chem Biol. 2012 Apr 20;7(4):672-7. 2. Song Y, et al. Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new ROR? inverse agonists: Virtual screening, structure-based optimization, and biological evaluation. Eur J Med Chem. 2016 Jun 30;116:13-26.