TargetMol

SR 3677 dihydrochloride

Product Code:
 
TAR-T35828
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T35828-5mg5mg£850.00
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Quantity:
TAR-T35828-50mg50mg£1,661.00
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Quantity:
TAR-T35828-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).
CAS:
1781628-88-3
Formula:
C22H24N4O4.2HCl
Molecular Weight:
481.37
Purity:
0.98
SMILES:
O=C(C3COC(C=CC=C4)=C4O3)NC1=CC=C(C2=CNN=C2)C=C1OCCN(C)C.Cl.Cl

References

Feng et al (2008) Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J.Med.Chem. 51 6642 PMID:18834107