TargetMol

MB 0223

Product Code:
 
TAR-T37023
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T37023-5mg5mg£850.00
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Quantity:
TAR-T37023-50mg50mg£1,661.00
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Quantity:
TAR-T37023-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Dynamin-related GTPase DRP1 partial inhibitor (IC50 = 1.2 μM). Selective for DRP1 over other dynamin-related GTPases, OPA1 and DYN1. Increases mitochondrial DNA levels in mfn1- knockout MEFs deficient in mitochondrial fusion.
CAS:
2247732-89-2
Formula:
C26H27N5OS
Molecular Weight:
457.59
Purity:
0.98
SMILES:
CC1=CN(C(C(NC2=CC=C(C3=CN=CC=C3)C=C2)=O)=C1)CC4=CSC(N5CCCCC5)=N4

References

Mallat et al (2018) Discovery and characterization of selective small molecule inhibitors of the mammalian mitochondrial division dynamin, DRP1. Biochem.Biophys.Res.Commun. 499 556 PMID:29601815