TargetMol

8-Hydroxyguanine

Product Code:
 
TAR-T19165
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19165-1mg1mg£122.00
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TAR-T19165-5mg5mg£195.00
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TAR-T19165-10mg10mg£254.00
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TAR-T19165-25mg25mg£383.00
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TAR-T19165-50mg50mg£531.00
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Quantity:
TAR-T19165-100mg100mg£726.00
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Quantity:
TAR-T19165-500mg500mg£1,380.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
8-Hydroxyguanine is a major pre-mutagenic lesion generated from reactive oxygen species and causes G-T and A-C substitutions.
CAS:
5614-64-2
Formula:
C5H5N5O2
Molecular Weight:
167.128
Pathway:
Metabolism
Purity:
0.98
SMILES:
Nc1nc2[nH]c(=O)[nH]c2c(=O)[nH]1
Target:
Endogenous Metabolite

References

1. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. 2. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. 3. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.