TargetMol

Nilotinib monohydrochloride monohydrate

Product Code:
 
TAR-T2147
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2147-1mL1 mL * 10 mM (in DMSO)£95.00
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TAR-T2147-50mg50mg£97.00
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TAR-T2147-100mg100mg£108.00
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TAR-T2147-200mg200mg£118.00
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TAR-T2147-500mg500mg£164.00
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This product comes from: United States.
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Further Information

Bioactivity:
Nilotinib monohydrochloride monohydrate is significantly potent BCR-ABL against, is a second generation tyrosine kinase inhibitor (TKI), and is active against many BCR-ABL mutants.
CAS:
923288-90-8
Formula:
C28H25ClF3N7O2
Molecular Weight:
584
Pathway:
Cytoskeletal Signaling; Tyrosine Kinase/Adaptors; Autophagy; Angiogenesis
Purity:
0.997
SMILES:
O.Cl.Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F
Target:
Bcr-Abl; Autophagy

References

1. Sako H , Fukuda K , Saikawa Y , et al. Antitumor Effect of the Tyrosine Kinase Inhibitor Nilotinib on Gastrointestinal Stromal Tumor (GIST) and Imatinib-Resistant GIST Cells[J]. PLOS ONE, 2014, 9(9):e107613. 2. Gozde Dervis Hakim Mujde Soyturk Mehtat Unlu Pinar Ataca Meral Karaman Ozgul Sagol Elif Borekci Osman Yilmaz. Mucosal healing effect of nilotinib in indomethacin-induced enterocolitis:A rat model[J]. 2015.