TargetMol

Cinnamaldehyde

Product Code:
 
TAR-T4S1551
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T4S1551-1mL1 mL * 10 mM (in DMSO)£111.00
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Further Information

Bioactivity:
1. Cinnamaldehyde has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the expression of miR-27a. 4. Cinnamaldehyde induces the generation of reactive oxygen species and exerts vasodilator and anticancer effects. 5. Cinnamaldehyde appears to be a promising candidate as an adjuvant in combination therapy with 5-fluorouracil (5-FU) and oxaliplatin (OXA), two chemotherapeutic agents used in CRC treatment. The possible mechanisms of its action may involve the regulation of drugmetabolizing genes. 6. Cinnamaldehyde plays a certain role in inhibiting the occurrence and progression of melanoma and its action mechanism may be manifested by inhibiting expression of VEGF and HIF-α, thus blood vessel simulation and formation of new blood vessels of melanoma cells, and growth of tumors accordingly.
CAS:
104-55-2
Formula:
C9H8O
Molecular Weight:
132.162
Pathway:
Chromatin/Epigenetic; Angiogenesis
Purity:
0.85
SMILES:
O=CC=Cc1ccccc1
Target:
HIF

References

Cao L, Xu E, Zheng R, et al. Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages. Chinese Medicine. 2022, 17(1): 1-16. Raffai, G?bor, Kim B , Park S , et al. Cinnamaldehyde and cinnamaldehyde-containing micelles induce relaxation of isolated porcine coronary arteries: role of nitric oxide and calcium[J]. International Journal of Nanomedicine, 2014.