TargetMol

Azetidine-2-carboxylic acid

Product Code:
 
TAR-T8100
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8100-100mg100mg£104.00
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Further Information

Bioactivity:
Azetidine-2-carboxylic acid is a non proteinogenic amino acid homologue of proline found in common beets. Azetidine-2-carboxylic acid can be misincorporated into proteins in place of proline in many species, including humans. It is a toxic and teratogenic agent[1][2].
CAS:
2517-04-6
Formula:
C4H7NO2
Molecular Weight:
101.105
Purity:
0.98
SMILES:
OC(=O)C1CCN1

References

Rubenstein E, et al. Misincorporation of the proline analog azetidine-2-carboxylic acid in the pathogenesis of multiple sclerosis: a hypothesis. J Neuropathol Exp Neurol. 2008 Nov;67(11):1035-40. Rubenstein E, et al. Azetidine-2-carboxylic acid in the food chain. Phytochemistry. 2009 Jan;70(1):100-4. Lane JM, et al. Effect of the proline analogue azetidine-2-carboxylic acid on collagen synthesis in vivo. I. Arrest of collagen accumulation in growing chick embryos. Biochim Biophys Acta. 1971 Jun 29;236(3):517-27.