TargetMol

PMPA sodium

Product Code:
 
TAR-T25968
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T25968-5mg5mg£850.00
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Quantity:
TAR-T25968-50mg50mg£1,661.00
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Quantity:
TAR-T25968-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
PMPA sodium is a potent and selective glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase) inhibitor.
CAS:
373645-42-2
Formula:
C6H7Na4O7P
Molecular Weight:
314.048
Purity:
0.98
SMILES:
[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CCC(CP([O-])([O-])=O)C([O-])=O

References

1. Rais R, Jiang W, Zhai H, Wozniak KM, Stathis M, Hollinger KR, Thomas AG, Rojas C, Vornov JJ, Marohn M, Li X, Slusher BS. FOLH1/GCPII is elevated in IBD patients, and its inhibition ameliorates murine IBD abnormalities. JCI Insight. 2016 Aug 4;1(12). pii: e88634. PubMed PMID: 27536732; PubMed Central PMCID: PMC4985244. 2. Sol?nov? V, Kasicka V, S?zelov? P, Hol? A. Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector. Electrophoresis. 2009 Jun;30(12):2245-54. doi: 10.1002/elps.200800790. PubMed PMID: 19544492. 3. Saxena BB, Han YA, Fu D, Rathnam P, Singh M, Laurence J, Lerner S. Sustained release of microbicides by newly engineered vaginal rings. AIDS. 2009 May 15;23(8):917-22. doi: 10.1097/QAD.0b013e32832af57c. PubMed PMID: 19381077. 4. Richardson DD, Caruso JA. Derivatization of organophosphorus nerve agent degradation products for gas chromatography with ICPMS and TOF-MS detection. Anal Bioanal Chem. 2007 Jun;388(4):809-23. Epub 2007 Mar 14. PubMed PMID: 17356819.