TargetMol

TRAF-STOP inhibitor 6877002

Product Code:
 
TAR-T17157
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17157-5mg5mg£105.00
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TAR-T17157-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T17157-10mg10mg£119.00
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TAR-T17157-25mg25mg£177.00
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TAR-T17157-50mg50mg£266.00
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TAR-T17157-100mg100mg£342.00
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Quantity:
TAR-T17157-200mg200mg£470.00
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This product comes from: United States.
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Further Information

Bioactivity:
TRAF-STOP inhibitor 6877002, is a selective inhibitor of CD40-TRAF6 interaction. TRAF-STOP 6877002 reduces leukocyte recruitment, and reduces macrophage activation; reduces macrophage proliferation in atherosclerotic plaques.
CAS:
433249-94-6
Formula:
C17H17NO
Molecular Weight:
251.329
Pathway:
NF-κb
Purity:
0.98
SMILES:
Cc1ccc(C)c(NC=CC(=O)c2ccccc2)c1
Target:
NF-κB

References

Seijkens TTP, et al. Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis. J Am Coll Cardiol. 2018 Feb 6;71(5):527-542.