Elabscience

IDO2 Polyclonal Antibody

Product Code:
 
E-AB-18375
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450
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Immunohistochemistry of paraffin-embedded Human brain tissue using IDO2 Polyclonal Antibody at dilution of 1:45(?200)
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Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human brain tissue using IDO2 Polyclonal Antibody at dilution of 1:45(?200)

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Further Information

Abbreviation:
IDO2
Background:
INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
45 kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
3-dioxygenase 2;3-dioxygenase-like protein 1;EC 1.13.11.;I23O2;IDO 2;IDO-2;Ido2;INDOL 1;Indoleamine 2;Indoleamine 2;3 dioxygenase 2;Indoleamine 2;3 dioxygenase like 1 protein;Indoleamine 2;3 dioxygenase like protein 1;Indoleamine pyrrole 2;3 dioxygenase like 1;Indoleamine pyrrole 2;3 dioxygenase like protein 1;Indoleamine-pyrrole 2
UNIProt ID:
Q6ZQW0

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