Elabscience

Recombinant Cavia porcellus CTLA-4/CD152 Protein (His Tag)

Product Code:
 
PKSQ050093
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Guinea Pig
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
 
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt store it immediately at < -20°C.
Storage:
 
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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CodeSizePrice
PKSQ050093-10ug10ug£288.00
Quantity:
PKSQ050093-50ug50ug£436.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
CTLA-4;CD152
Accession:
H0VUB1
Activity:
Immobilized Mouse B7-1-Fc(Cat: PKSM041366) at 1ug/ml(100 ul/well) can bind Cavia porcellus CTLA-4-His. The ED50 of Cavia porcellus CTLA-4-His is 0.17ug/ml.
Background:
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
Calculated MW:
14.1 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
P.Pichia
Formulation:
Supplied as a 0.2 um filtered solution of PBS, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
18-40 kDa
Purity:
> 90 % as determined by reducing SDS-PAGE.
Sequence:
Ala37-Asp161
Target Synonym:
Cytotoxic T-lymphocyte protein 4;Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD152;CTLA4
UNIProt ID:
H0VUB1

Documents