Elabscience

Recombinant Human JAM-A/F11R Protein (His Tag)

Product Code:
 
PKSH033607
Product Group:
 
Recombinant Proteins
Supplier:
 
Elabscience
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
This product is provided as lyophilized powder which is shipped with ice packs.
Storage:
 
Generally lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
 

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CodeSizePrice
PKSH033607-10ug10ug£180.00
Quantity:
PKSH033607-50ug50ug£378.00
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This product comes from: China.
Typical lead time: 14-21 working days.
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Further Information

Abbreviation:
JAM-A;F11R
Accession:
Q9Y624
Background:
Junctional Adhesion Molecule A (JAM-A) is a single-pass type I membrane protein that belongs to the immunoglobulin superfamily. JAM-A contains 2 Ig-like V-type (immunoglobulin-like) domains and Interacts with the ninth PDZ domain. JAM-A is localized to the tight junctions of both epithelial and endothelial cells. JAM-A seems to be involved in epithelial tight junction formation. JAM-A appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM-A, thereby preventing tight junction assembly. JAM-A plays a role in regulating monocyte transmigration involved in regulating integrity of the epithelial barrier. In the case of orthoreovirus infection, JAM-A serves as receptor for the virus.
Calculated MW:
23.89 kDa
Endotoxin:
< 1.0 EU per ug of the protein as determined by the LAL method.
Expression Host:
HEK293 Cells
Formulation:
Lyophilized from a 0.2 um filtered solution of 20mM Tris-HCl, 150mM NaCl, 100mM Glycine, pH 7.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Fusion tag:
C-His
ObservedMW:
28-31 kDa
Purity:
> 95 % as determined by reducing SDS-PAGE.
Sequence:
Ser28-Val238
Target Synonym:
Junctional Adhesion Molecule A;JAM-A;Junctional Adhesion Molecule 1;JAM-1;Platelet F11 Receptor;Platelet Adhesion Molecule 1;PAM-1;CD321;F11R;JAM1;JCAM;JAMA;JCAM;KAT
UNIProt ID:
Q9Y624

Documents