Elabscience

CD177 Polyclonal Antibody

Product Code:
 
E-AB-61208
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of BT-474 cells using CD177 Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of BT-474 cells using CD177 Polyclonal Antibody at dilution of 1:1000.

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E-AB-61208-60uL60uL£210.00
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E-AB-61208-120uL120uL£291.00
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E-AB-61208-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
CD177
Background:
This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
15kDa/27kDa/46kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CD177 (NP_065139.2).
ObservedMW:
45kDa
Purification method:
Affinity purification
Target Synonym:
CD177;HNA-2a;HNA2A;NB1;NB1 GP;PRV-1;PRV1;NB1GP
UNIProt ID:
Q8N6Q3

Documents