Elabscience

ZFAND5 Polyclonal Antibody

Product Code:
 
E-AB-90603
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of mouse eye using ZFAND5 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of mouse eye using ZFAND5 Polyclonal Antibody at 1:1000 dilution.

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CodeSizePrice
E-AB-90603-60uL60uL£210.00
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E-AB-90603-120uL120uL£291.00
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E-AB-90603-200uL200uL£431.00
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Further Information

Abbreviation:
ZFAND5
Background:
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF, IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
23kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant fusion protein of human ZFAND5
ObservedMW:
23kDa
Purification method:
Affinity purification
Target Synonym:
ZFAND5;ZA20D2;ZFAND5A;ZNF216
UNIProt ID:
O76080

Documents