Diaclone

Human CD130 ELISA Kit

Product Code:
 
850.520.192
Product Group:
 
ELISA Kits
Supplier:
 
Diaclone
Host Type:
 
Human
Regulatory Status:
 
RUO
 

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850.520.1922 x 96 (pre-coated)£570.00
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  • Further Information
  • References
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Further Information

Antigen Synonyms:
gp130
Assay Range:
56.25-1800 pg/ml
Cross reaction:
No cross reactivity with other human soluble receptors. No interference with neither soluble gp80 nor IL-6.
Description:
Diaclone ELISA Kits include pre-coated strip plates biotinylated secondary antibody standards controls (where applicable) buffers streptavidin-HRP TMB stop reagents and a detailed procedure.
Detection Target:
CD130 / gp130
Incubation:
1h45
Reactivity:
Human
Research Area:
Cytokine / Chemokine Receptors
Sample Size:
100 µl
Sample Types:
Serum Plasma Cell culture supernatant
Sensitivity:
15 pg/ml
Specificity:
Recognizes both natural and recombinant human soluble gp130

References

  1. Arranz-Valsero I. et al.Mol Vis.2013;19: 85-99. Involvement of corneal epithelial cells in the Th17 response in an in vitro bacterial inflammation model. https://www.ncbi.nlm.nih.gov/pubmed/23378722
  2. Corbi P. et al. Eur J Cardiothorac Surg. 2000; 18(1): 98 - 103. Circulating soluble gp130 soluble IL-6R and IL-6 in patients undergoing cardiac surgery with or without extracorporeal circulation. https://www.ncbi.nlm.nih.gov/pubmed/10869947
  3. Dore P. et al. Clin Exp Immunol.1997; 107(1): 182-8. IL-6 and soluble IL-6 receptors (sIL-6R and sgp130) in human pleural effusions: massive IL-6 production independently of underlying diseases. https://www.ncbi.nlm.nih.gov/pubmed/9010274
  4. Gougelet A. et al. PLoS One2009; 4(11): e8026. Lymphoma and myeloma cell resistance to cytotoxic agents and ionizing radiations is not affected by exposure to anti-IL-6 antibody.. https://www.ncbi.nlm.nih.gov/pubmed/19956602
  5. Muller-Newen G. et al. J Immunol. 1998;161(11): 6347-55.. Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. https://www.ncbi.nlm.nih.gov/pubmed/9834125
  6. Santer F. R. et al. Endocr. Relat. Cancer 2010;17(1): 241-253.. Interleukin-6 trans-signalling differentially regulates proliferation migration adhesion and maspin expression in human prostate cancer cells. https://www.ncbi.nlm.nih.gov/pubmed/19966016