NSJ Bioreagents

PD-L1 Antibody / B7-H1 / CD274

Product Code:
 
NSJ-V5291SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit IgG, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
PDL1/8222R
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Aliquot the PD-L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
1 / 2
Western blot testing of human HDLM-2 cell lysate with PD-L1 antibody (clone PDL1/8222R). Predicted molecular weight ~34 kDa (unmodified), 45-70 kDa (glycosylated).~
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IHC staining of FFPE human tonsil tissue with PD-L1 antibody (clone PDL1/8
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Western blot testing of human HDLM-2 cell lysate with PD-L1 antibody (clone PDL1/8222R). Predicted molecular weight ~34 kDa (unmodified), 45-70 kDa (glycosylated).~
IHC staining of FFPE human tonsil tissue with PD-L1 antibody (clone PDL1/8

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NSJ-V5291SAF-100UG100 ug£534.00
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Further Information

Application Details:
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
Description:
PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancers ability to evade the immune system.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the PD-L1 antibody.
Limitation:
This PD-L1 antibody is available for research use only.
Localization:
Cell Surface, Cytoplasm
Purity:
Protein A/G affinity
Uniprot #:
Q9NZQ7

Documents