TargetMol

Glutathione arsenoxide hydrochloride

Product Code:
 
TAR-T27417L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T27417L-1mg1mg£352.00
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TAR-T27417L-5mg5mg£736.00
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TAR-T27417L-1mL1 mL * 10 mM (in DMSO)£783.00
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TAR-T27417L-10mg10mg£978.00
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TAR-T27417L-25mg25mg£1,348.00
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TAR-T27417L-50mg50mg£1,661.00
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TAR-T27417L-100mg100mg£2,079.00
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TAR-T27417L-500mg500mg£4,006.00
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This product comes from: United States.
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Further Information

Bioactivity:
Glutathione arsenoxide hydrochloride is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride targets the mitochondrial inner membrane adenine nucleotidyl transferase (ANT), which inhibits cell proliferation and promotes apoptosis. Glutathione arsenoxide hydrochloride can be used to recognize cell surface proteins such as protein disulfide isomerases.
CAS:
T27417L
Molecular Weight:
584.86
Pathway:
Apoptosis|Neuroscience
Purity:
0.971
SMILES:
OC([C@H](CCC(N[C@@H](CSCC(NC1=CC=C([As](O)O)C=C1)=O)C(NCC(O)=O)=O)=O)N)=O.Cl
Target:
Apoptosis|AChR

References

Dilda PJ, et al. Para to ortho repositioning of the arsenical moiety of the angiogenesis inhibitor 4-(N-(S-glutathionylacetyl)amino)phenylarsenoxide results in a markedly increased cellular accumulation and antiproliferative activity. Cancer Res. 2005 ; 65(24):11729-11734. Park D, et al. The tumour metabolism inhibitors GSAO and PENAO react with cysteines 57 and 257 of mitochondrial adenine nucleotide translocase. Cancer Cell Int. 2012 ; 12(1):11. Habeck M. Australian scientists design novel antiangiogenic weapon. The Lancet Oncology. 2000 ; 1(4): 199.