TargetMol

DP-1 hydrochloride

Product Code:
 
TAR-T38961L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
❮❯

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CodeSizePrice
TAR-T38961L-1mg1mg£209.00
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TAR-T38961L-5mg5mg£410.00
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TAR-T38961L-1mL1 mL * 10 mM (in DMSO)£444.00
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TAR-T38961L-10mg10mg£574.00
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TAR-T38961L-25mg25mg£858.00
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TAR-T38961L-50mg50mg£1,139.00
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Quantity:
TAR-T38961L-100mg100mg£1,508.00
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Quantity:
TAR-T38961L-500mg500mg£2,986.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DP-1 hydrochloride is a degradation product of SDC-TRAP-0063, a fragment of Ganetespib, a heat shock protein 90 (HSP90) inhibitor with antitumor activity.
CAS:
1472616-35-5
Molecular Weight:
498.02
Pathway:
Metabolism
Purity:
0.9929
SMILES:
Cl.O=C1NN=C(C=2C=C(C(O)=CC2O)C(C)C)N1C=3C=CC4=C(C=CN4CCC5CCNCC5)C3
Target:
Drug Metabolite

References

Chimmanamada DU, et al. Targeted therapeutics. US20140079636A1. Ishida H, et al. Identification and characterization of novel isoforms of human DP-1: DP-1{alpha} regulates the transcriptional activity of E2F1 as well as cell cycle progression in a dominant-negative manner. J Biol Chem. 2005;280(26):24642-24648. Helin K, et al. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev. 1993;7(10):1850-1861.