TargetMol

HTS07545

Product Code:
 
TAR-T61316
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T61316-1mg1mg£101.00
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TAR-T61316-5mg5mg£142.00
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TAR-T61316-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T61316-10mg10mg£189.00
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TAR-T61316-25mg25mg£309.00
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TAR-T61316-50mg50mg£454.00
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TAR-T61316-100mg100mg£622.00
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TAR-T61316-500mg500mg£1,259.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
HTS07545 is a potent sulfide:quinone oxidoreductase inhibitor (IC50: 30 nM).HTS07545 reduces the rate of hydrogen sulfide (H2S) decomposition.HTS07545 has been used in heart failure studies.
CAS:
118666-03-8
Molecular Weight:
358.39
Pathway:
Metabolism
Purity:
0.98
SMILES:
N#CC1=C(N=C(C=C1C=2C=CC=CC2)C=3C=CC=CC3)OCC(=O)OCC
Target:
NADPH

References

Baugh SDP, et al. Synthesis and evaluation of potent novel inhibitors of human sulfide:quinone oxidoreductase. Bioorg Med Chem Lett. 2021;54:128443.