TargetMol

MDL-800

Product Code:
 
TAR-T64529
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T64529-1mg1mg£111.00
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TAR-T64529-5mg5mg£167.00
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TAR-T64529-10mg10mg£213.00
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TAR-T64529-25mg25mg£312.00
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TAR-T64529-50mg50mg£433.00
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TAR-T64529-100mg100mg£603.00
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Quantity:
TAR-T64529-500mg500mg£1,187.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.
CAS:
2275619-53-7
Molecular Weight:
626.3
Pathway:
DNA Damage/DNA Repair|Chromatin/Epigenetic
Purity:
0.98
SMILES:
O=C(OC)C1=CC(=CC=C1S(=O)(=O)NC2=CC(Br)=C(F)C=C2C)NS(=O)(=O)C=3C=C(Cl)C=C(Cl)C3
Target:
Sirtuin

References

Jiang X, et al. MDL-800, the SIRT6 Activator, Suppresses Inflammation via the NF-?B Pathway and Promotes Angiogenesis to Accelerate Cutaneous Wound Healing in Mice. Oxid Med Cell Longev. 2022 Apr 27;2022:1619651. Shang JL, et al. MDL-800, an allosteric activator of SIRT6, suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer. Acta Pharmacol Sin. 2021 Jan;42(1):120-131.