TargetMol

(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride

Product Code:
 
TAR-T67699L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67699L-1mg1mg£227.00
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TAR-T67699L-5mg5mg£424.00
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TAR-T67699L-10mg10mg£591.00
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TAR-T67699L-25mg25mg£863.00
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TAR-T67699L-50mg50mg£1,187.00
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TAR-T67699L-100mg100mg£1,572.00
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Quantity:
TAR-T67699L-500mg500mg£3,066.00
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Further Information

Bioactivity:
(R)-1-(2-((2-methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide hydrochloride possesses anti-apoptotic, anti-proliferative and anti-tumour activities.
CAS:
T67699L
Molecular Weight:
621.09
Pathway:
Apoptosis
Purity:
0.9752
SMILES:
O=C([C@H]1CN(C2=CC(NC3=CC=C(N4CCNCC4)C=C3OC)=NC=C2)CCC1)NCC5=CC=C(OC(F)(F)F)C=C5.[H]Cl
Target:
Apoptosis

References

Liu S, et al. Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors. European Journal of Medicinal Chemistry, 2019, 179: 358-375.