TargetMol

ThioLox

Product Code:
 
TAR-T67908
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67908-1mg1mg£119.00
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TAR-T67908-5mg5mg£189.00
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TAR-T67908-10mg10mg£254.00
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TAR-T67908-25mg25mg£414.00
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Quantity:
TAR-T67908-50mg50mg£584.00
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Quantity:
TAR-T67908-100mg100mg£785.00
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Quantity:
TAR-T67908-500mg500mg£1,540.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
ThioLox is a competitive 15-lipoxygenase-1 (15-LOX-1) inhibitor with IC50 value of 12 uM. ThioLox shows anti-inflammatory and neuroprotective properties. It has anti-inflammatory and neuroprotective effects, and has a strong protective effect against glutamate toxicity.
CAS:
1202193-89-2
Molecular Weight:
274.38
Pathway:
Metabolism
Purity:
1
SMILES:
CCCCNC(=O)C1=C(SC(=C1)C2=CC=CC=C2)N
Target:
Lipoxygenase

References

Eleftheriadis N,et al. Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. Eur J Med Chem. 2016;122:786-801.