TargetMol

JB062

Product Code:
 
TAR-T67952
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T67952-1mg1mg£227.00
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Quantity:
TAR-T67952-1mL1 mL * 10 mM (in DMSO)£458.00
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TAR-T67952-5mg5mg£464.00
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TAR-T67952-10mg10mg£645.00
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TAR-T67952-25mg25mg£946.00
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TAR-T67952-50mg50mg£1,259.00
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Quantity:
TAR-T67952-100mg100mg£1,661.00
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Quantity:
TAR-T67952-500mg500mg£3,259.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
JB062 is a nonmuscle myosin inhibitor with IC 50 values of 1.6, 5.4, and >100 uM for Skeletal muscle myosin , Cardiac muscle myosin , and Smooth muscle myosin II, respectively. JB062 has cytotoxic to human cancer cells but not normal cells. JB062 can be used in research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy .
CAS:
2417988-00-0
Molecular Weight:
323.34
Pathway:
Cytoskeletal Signaling
Purity:
0.9949
SMILES:
O=C1OC=2C=CC=CC2C(O)=C1C(=NCC3=CC=C(OC)C=C3)C
Target:
Myosin

References

Smith JD, et al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2023;247:115008.