TargetMol

Ezlopitant

Product Code:
 
TAR-T68068
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T68068-1mg1mg£139.00
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TAR-T68068-5mg5mg£239.00
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TAR-T68068-10mg10mg£319.00
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TAR-T68068-25mg25mg£541.00
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TAR-T68068-50mg50mg£697.00
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TAR-T68068-100mg100mg£946.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Ezlopitant is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain.
CAS:
147116-64-1
Molecular Weight:
454.65
Pathway:
GPCR/G Protein|Neuroscience
Purity:
0.9703
SMILES:
C([C@H]1[C@@H](NCC2=C(OC)C=CC(C(C)C)=C2)C3CCN1CC3)(C4=CC=CC=C4)C5=CC=CC=C5
Target:
Neurokinin receptor

References

Obach RS. Mechanism of cytochrome P4503A4- and 2D6-catalyzed dehydrogenation of ezlopitant as probed with isotope effects using five deuterated analogs. Drug Metab Dispos. 2001 Dec;29(12):1599-607. Reed-Hagen AE, et al. Pharmacokinetics of ezlopitant, a novel non-peptidic neurokinin-1 receptor antagonist in preclinical species and metabolite kinetics of the pharmacologically active metabolites. Biopharm Drug Dispos. 1999 Dec;20(9):429-39.