TargetMol

CHBO4

Product Code:
 
TAR-T77578
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77578-1mg1mg£112.00
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TAR-T77578-5mg5mg£166.00
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TAR-T77578-10mg10mg£211.00
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TAR-T77578-25mg25mg£307.00
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TAR-T77578-50mg50mg£426.00
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TAR-T77578-100mg100mg£595.00
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Quantity:
TAR-T77578-500mg500mg£1,187.00
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Further Information

Bioactivity:
CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 uM, and the Ki value was 0.010 ? 0.005 uM.CHBO4 reduces cellular damage by scavenging intracellular reactive oxygen species (ROS), and can be used to study Parkinson's disease (PD).
CAS:
98991-32-3
Molecular Weight:
305.14
Pathway:
Metabolism|Immunology/Inflammation|Neuroscience
Purity:
0.98
SMILES:
O=C(C=CC1=CC=C(F)C=C1)C2=CC=C(Br)C=C2
Target:
MAO|ROS

References

Thomas Parambi DG, et al. Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study. Comput Biol Chem. 2023;105:107899.