TargetMol

BTM-3566

Product Code:
 
TAR-T77713
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T77713-1mg1mg£227.00
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Quantity:
TAR-T77713-5mg5mg£458.00
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Quantity:
TAR-T77713-10mg10mg£626.00
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TAR-T77713-25mg25mg£938.00
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Quantity:
TAR-T77713-50mg50mg£1,267.00
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Quantity:
TAR-T77713-100mg100mg£1,653.00
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Quantity:
TAR-T77713-500mg500mg£3,227.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to study DLBCL.
CAS:
2228857-70-1
Molecular Weight:
525.58
Pathway:
Apoptosis
Purity:
0.98
SMILES:
O=C(O)C1=C(C=2C=CC=C(F)C2)C(=NN1C3=NC(=C(S3)SC(C)C)C4=CCC(CC4)C(F)(F)F)C
Target:
Apoptosis

References

Schwarzer A, et al. Targeting aggressive B-cell lymphomas through pharmacological activation of the mitochondrial protease OMAMol Cancer Ther. 2023 Aug 30. Adrian Schwarzer, et al. Btm-3566, a Novel Activator of the Mitochondrial Stress Response Promotes Robust Therapeutic Responses in Vitro and In Vivo in Diffuse Large B-Cell Lymphoma. Blood. Volume 138, Supplement 1, 23 November 2021, Page 684.