TargetMol

Apogossypolone (ApoG2)

Product Code:
 
TAR-T21786
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T21786-5mg5mg£850.00
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Quantity:
TAR-T21786-50mg50mg£1,661.00
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Quantity:
TAR-T21786-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i values of 35, 25 and 660 nM for Bcl-2, Mcl-1 and Bcl-X L, respectively. Apogossypolone shows antitumor activities, induces cell apoptosis [1] and autophagy [2]. Apogossypolone also has antifungal activity [3].
CAS:
886578-07-0
Molecular Weight:
979
Purity:
0.98
SMILES:
CC(C)c1c(O)c(O)cc2C(=O)C(=C(C)C(=O)c12)C1=C(C)C(=O)c2c(cc(O)c(OCC(C)c3c(O)c(O)cc4C(=O)C(=C(C)C(=O)c34)C3=C(C)C(=O)c4c(cc(O)c(O)c4C(C)C)C3=O)c2C(C)C)C1=O