TargetMol

Anticancer agent 73

Product Code:
 
TAR-T60420
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T60420-5mg5mg£108.00
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Quantity:
TAR-T60420-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T60420-10mg10mg£135.00
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TAR-T60420-25mg25mg£201.00
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TAR-T60420-50mg50mg£269.00
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Quantity:
TAR-T60420-100mg100mg£366.00
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This product comes from: United States.
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Further Information

Bioactivity:
Anticancer agent 73 is an anticancer agent which potently targets transactivation response(TAR) RNA-binding protein 2 (TRBP) and disrupts the TRBP-Dicer interaction. Anticancer agent 73 suppresses the growth and metastasis of HCC in vitro and in vivo by modulating expression profiles of miRNAome and proteome in HCC cells.
CAS:
124811-87-6
Formula:
C14H15NO4
Molecular Weight:
261.27
Pathway:
DNA Damage/DNA Repair|Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
O=C(OCC)C=1N=C(OC1C)C=2C=CC(OC)=CC2
Target:
DNA/RNA Synthesis

References

Peng T, et al. Discovery of a Novel Small-Molecule Inhibitor Disrupting TRBP-Dicer Interaction against Hepatocellular Carcinoma via the Modulation of microRNA Biogenesis. J Med Chem. 2022;65(16):11010-11033.