TargetMol

JMI-105

Product Code:
 
TAR-T61058
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T61058-5mg5mg£850.00
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Quantity:
TAR-T61058-50mg50mg£1,661.00
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Quantity:
TAR-T61058-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
JMI-105 has the potential as an antimalarial agent. JMI-105 is a potent inhibitor of Plasmodium falciparum falcipain-2 protease (PfFP-2) that inhibits the P. falciparum strains CQ S (3D7) and CQ R (RKL-9) growth with IC 50 values of 8.8 uM and 14.3 uM. In a murine model with P. berghei ANKA infection, JMI-105 significantly decreases parasitemia and prolonged host survival [1].
CAS:
2227315-30-0
Formula:
C20H23N3O2
Molecular Weight:
337.423
Purity:
0.98
SMILES:
COc1ccc(cc1)-n1cc(COc2cc(ccc2C)C(C)C)nn1