TargetMol

ALK5-IN-8

Product Code:
 
TAR-T61203
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1

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CodeSizePrice
TAR-T61203-5mg5mg£270.00
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Quantity:
TAR-T61203-50mg50mg£1,066.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T61203-100mg100mg£1,669.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways (taken from patent WO2021190425A1, compound 1) [1].
CAS:
2705900-81-6
Molecular Weight:
350.353
Purity:
0.98
SMILES:
CCOC(=O)c1cnn2ccc(cc12)-c1c[nH]nc1-c1ccc(F)cc1