TargetMol

G12Si-5

Product Code:
 
TAR-T64059
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
 

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CodeSizePrice
TAR-T64059-5mg5mg£850.00
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Quantity:
TAR-T64059-50mg50mg£1,661.00
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Quantity:
TAR-T64059-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
G12Si-5 is a covalent inhibitor of the K-RasG12S mutant with a Ki value of 26 uM. G12Si-5 binds to the S-IIP structural domain and inhibits oncogenic signalling. g12Si-5 reduces ERK phosphorylation levels in KRAS G12S mutant cells.
CAS:
2946593-46-8
Formula:
C31H29ClFN5O3
Molecular Weight:
574.04
Purity:
0.98
SMILES:
C(OC=1N=C(C2=C(N1)C(F)=C(N=C2)C=3C4=C(C=CC3)C=CC=C4Cl)N5C[C@]6([C@@](CC5)(C(=O)O6)[H])[H])C78N(CCC7)CCC8