TargetMol

AChE/GSK-3β-IN-1

Product Code:
 
TAR-T64143
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T64143-5mg5mg£850.00
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Quantity:
TAR-T64143-50mg50mg£1,661.00
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Quantity:
TAR-T64143-100mg100mg£2,079.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-3β (IC50: 22.4 nM). AChE/GSK-3β-IN-1 is able to occupy the ATP binding site of DYRK1A. aChE/GSK-3β-IN-1 exhibits high kinase selectivity for the CMGC kinase family. aChE/GSK-3β-IN-1 inhibits ROS expression and reduces oxidative stress. aChE/GSK-3β-IN-1 can be used to study Alzheimer's disease.
CAS:
2412364-73-7
Molecular Weight:
585.73
Purity:
0.98
SMILES:
CNC(=O)c1sc(nc1OCC1CC1)-c1ccnc(NC(=O)CNCCNc2c3CCCCc3nc3ccccc23)c1