TargetMol

Naldemedine tosylate

Product Code:
 
TAR-T70929
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T70929-5mg5mg£378.00
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TAR-T70929-50mg50mg£1,645.00
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Quantity:
TAR-T70929-100mg100mg£2,456.00
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This product comes from: United States.
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Further Information

Bioactivity:
Naldemedine (S-297995) tosylate is an orally active u-opioid receptor antagonist (PAMORA) . Naldemedine tosylate shows potent binding affinities ( K i =0.34, 0.43, 0.94 nM, respectively) and antagonist activities ( IC 50 =25.57, 7.09, 16.1 nM, respectively) for recombinant human u-, δ-, and κ- opioid receptors . Naldemedine can be used in opioid-induced constipation (OIC) research . Naldemedine tosylate is predicted to bind to 3CL pro encoded by SARS-CoV2 genome .
CAS:
1345728-04-2
Molecular Weight:
742.84
Purity:
0.98
SMILES:
S(=O)(=O)(O)C1=CC=C(C)C=C1.O[C@]12[C@@]34C=5C(O[C@]3(C(O)=C(C(NC(C)(C)C6=NC(=NO6)C7=CC=CC=C7)=O)C1)[H])=C(O)C=CC5C[C@]2(N(CC8CC8)CC4)[H]